Roberta Ferraldeschi Selected Research

ASTX-660

10/2021	Antagonism of inhibitors of apoptosis proteins reveals a novel, immune response-based therapeutic approach for T-cell lymphoma.
1/2020	A Phase I Study of ASTX660, an Antagonist of Inhibitors of Apoptosis Proteins, in Adults with Advanced Cancers or Lymphoma.

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Roberta Ferraldeschi Research Topics

Disease

23	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 09/2012
17	Neoplasms (Cancer) 10/2021 - 05/2007
4	Neoplasm Metastasis (Metastasis) 12/2016 - 03/2009
4	Breast Neoplasms (Breast Cancer) 06/2012 - 04/2010
3	Circulating Neoplastic Cells 01/2019 - 04/2011
2	Anemia 01/2020 - 10/2015
2	Diarrhea 01/2019 - 05/2009
2	Fatigue 01/2019 - 10/2015
2	Disease Progression 10/2015 - 09/2014
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 04/2011 - 10/2004
2	Colorectal Neoplasms (Colorectal Cancer) 05/2009 - 03/2009
1	T-Cell Lymphoma (Lymphoma, T Cell) 10/2021
1	Pneumonia (Pneumonitis) 01/2020
1	Exanthema (Rash) 01/2020
1	Hypotension (Low Blood Pressure) 01/2020
1	Lymphoma (Lymphomas) 01/2020
1	Lymphopenia (Lymphocytopenia) 01/2020
1	Melanoma (Melanoma, Malignant) 01/2018
1	Testicular Neoplasms (Testicular Cancer) 01/2018
1	Carcinogenesis 11/2015
1	Neutropenia 05/2009
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 05/2007
1	Esophageal Neoplasms (Esophageal Cancer) 01/2006

Drug/Important Bio-Agent (IBA)

9	Androgen Receptors (Androgen Receptor)IBA 01/2019 - 09/2012
8	abirateroneIBA 05/2018 - 01/2013
6	Docetaxel (Taxotere)FDA Link 05/2018 - 01/2013
4	Proteins (Proteins, Gene)FDA Link 10/2021 - 04/2015
4	Abiraterone AcetateIBA 01/2019 - 01/2013
4	Hormones (Hormone)IBA 01/2016 - 04/2015
4	AndrogensIBA 01/2016 - 01/2013
3	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 06/2012
3	Pharmaceutical PreparationsIBA 10/2016 - 01/2013
3	SteroidsIBA 11/2015 - 01/2013
2	ASTX-660IBA 10/2021 - 01/2020
2	EnzymesIBA 01/2020 - 07/2013
2	(2,4- dihydroxy- 5- isopropylphenyl)- (5- (4- methylpiperazin- 1- ylmethyl)- 1,3- dihydroisoindol- 2- yl)methanoneIBA 01/2019 - 01/2016
2	Messenger RNA (mRNA)IBA 01/2018 - 01/2016
2	AntigensIBA 01/2018 - 11/2017
2	Prostate-Specific Antigen (Semenogelase)IBA 11/2016 - 10/2015
2	Biomarkers (Surrogate Marker)IBA 10/2015 - 04/2011
2	Androgen Antagonists (Antiandrogens)IBA 01/2015 - 07/2013
2	GlucocorticoidsIBA 09/2014 - 07/2013
2	enzalutamideIBA 09/2014 - 03/2014
2	Tamoxifen FDA LinkGeneric 01/2011 - 04/2010
2	Irinotecan (Camptosar)FDA LinkGeneric 05/2009 - 03/2009
1	Inhibitor of Apoptosis ProteinsIBA 10/2021
1	ASTX029IBA 10/2021
1	Ribosomal Protein S6 Kinases (S6 Kinase)IBA 10/2021
1	Phosphotransferases (Kinase)IBA 01/2020
1	Actin Depolymerizing Factors (Cofilins)IBA 01/2020
1	Lipase (Acid Lipase)FDA Link 01/2020
1	AT13148IBA 01/2020
1	Decitabine FDA Link 01/2018
1	InterferonsIBA 01/2018
1	Azacitidine (5 Azacytidine)FDA Link 01/2018
1	dehydroacetic acid (DHAS)IBA 01/2018
1	CytokinesIBA 01/2018
1	guadecitabineIBA 01/2018
1	RNA (Ribonucleic Acid)IBA 01/2016
1	Amino Acids FDA Link 11/2015
1	Transcription Factors (Transcription Factor)IBA 11/2015
1	Protein Kinases (Protein Kinase)IBA 11/2015
1	TabletsIBA 10/2015
1	Adenosine Diphosphate Ribose (ADP-Ribose)IBA 10/2015
1	Adenosine Diphosphate (ADP)IBA 10/2015
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 10/2015
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 10/2015
1	olaparibIBA 10/2015
1	Cell-Free Nucleic AcidsIBA 10/2015
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 04/2015
1	TensinsIBA 04/2015
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 04/2015
1	PTEN Phosphohydrolase (PTEN Phosphatase)IBA 04/2015
1	Dexamethasone (Maxidex)FDA LinkGeneric 09/2014
1	Prednisolone (Predate)FDA LinkGeneric 09/2014
1	cabazitaxel FDA Link 09/2014
1	LigandsIBA 07/2013
1	Steroid Synthesis InhibitorsIBA 01/2013
1	Biological ProductsIBA 01/2013
1	Aromatase InhibitorsIBA 06/2012
1	Letrozole (Femara)FDA LinkGeneric 06/2012
1	ParaffinIBA 06/2012
1	Formaldehyde (Formol)FDA Link 06/2012
1	Aromatase (CYP19)IBA 06/2012
1	Caveolin 1IBA 04/2012
1	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 01/2011
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 03/2009
1	Fluorouracil (Carac)FDA LinkGeneric 03/2009
1	Leucovorin (Folinic Acid)FDA Link 03/2009
1	Pemetrexed (MTA)FDA Link 05/2007
1	Folic Acid AntagonistsIBA 05/2007
1	Carboplatin (JM8)FDA LinkGeneric 05/2007
1	Etoposide (VP 16)FDA LinkGeneric 05/2007

Therapy/Procedure

19	Castration 01/2019 - 09/2012
9	Therapeutics 10/2016 - 10/2004
7	Drug Therapy (Chemotherapy) 10/2016 - 10/2004
2	Radiotherapy 10/2016 - 10/2004
1	Immunotherapy 01/2018
1	Precision Medicine 05/2015
1	Esophagectomy 01/2006